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Article written by Richard Nkwenti; R.Ph, IMD, Ph.D; Hormone Restoration expert

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Estrogen dominance and how to eradicate it using Natural Bioidentical Progesterone and Low dose Naltrexone

Understanding Estrogen Dominance

Estrogen dominance is a condition that occurs when there is an imbalance between estrogen and progesterone levels in the body. This hormonal imbalance can affect both men and women and can have a significant impact on overall health and well-being. It is crucial to understand estrogen dominance and its effects in order to find effective solutions for addressing this hormonal imbalance.

Causes and Symptoms of Estrogen Dominance

Estrogen dominance can arise due to a variety of factors, including stress, environmental toxins, poor diet, and certain medications. These factors can disrupt the natural balance of hormones in the body, leading to an excess of estrogen relative to progesterone. This hormonal imbalance can manifest in various symptoms, including:

  1. Irregular menstrual cycles
  2. PMS symptoms, such as bloating, breast tenderness, and mood swings
  3. Weight gain, particularly in the hips and thighs
  4. Fatigue and low energy levels
  5. Increased risk of hormone-related cancers, such as breast and uterine cancer
  6. Mood disturbances, such as irritability and depression
  7. Fibrocystic breasts
  8. Hair loss or thinning
  9. Insomnia
  10. Digestive problems

If you are experiencing any of these symptoms, it is essential to consult with a healthcare professional to determine whether estrogen dominance may be a contributing factor. They can perform hormone level tests to assess your estrogen and progesterone levels and provide appropriate treatment options.

Addressing Estrogen Dominance with Natural Bioidentical Progesterone and Low Dose Naltrexone

To eradicate estrogen dominance and restore hormonal balance, many individuals turn to natural remedies such as bioidentical progesterone and low dose naltrexone (LDN). These treatments offer a more natural approach to hormone therapy and can help alleviate symptoms and restore hormonal balance without the side effects associated with conventional hormone replacement therapy (HRT).

Bioidentical progesterone: Bioidentical progesterone is a natural hormone that is identical in molecular structure to the progesterone produced by the human body. It can help rebalance estrogen levels and alleviate symptoms of estrogen dominance. Bioidentical progesterone is available in various forms, including creams, gels, and oral tablets, and should be used under the guidance of a healthcare professional.

Low dose naltrexone (LDN): LDN is an FDA-approved medication primarily used for the treatment of opioid addiction. However, research has shown that LDN can also have beneficial effects on the immune system and hormone balance. LDN has been found to modulate the immune response, reduce inflammation, and restore the balance between estrogen and progesterone. It is important to note that LDN should only be used under medical supervision and in accordance with a healthcare professional's guidance.

While bioidentical progesterone and LDN can offer significant benefits in addressing estrogen dominance, it is important to remember that each individual's hormonal needs are unique. Consulting with a healthcare professional who specializes in bioidentical hormone therapy can help determine the most appropriate treatment plan for addressing estrogen dominance and restoring hormonal balance.

Natural Bioidentical Progesterone

Estrogen dominance is a common hormonal imbalance that occurs when there is an excess of estrogen relative to progesterone in the body. This imbalance can lead to a variety of symptoms such as weight gain, mood swings, irregular periods, and more. One effective way to address estrogen dominance and restore hormonal balance is through the use of Natural Bioidentical Progesterone.

What is Natural Bioidentical Progesterone?

Natural Bioidentical Progesterone is a hormone that is derived from plant sources and is chemically identical to the progesterone produced naturally in the human body. Unlike synthetic progesterone or progestins, which have different molecular structures, bioidentical progesterone has the same structure as the progesterone produced by our bodies, making it more compatible and easily recognized.

How does Natural Bioidentical Progesterone help in balancing hormones?

Natural Bioidentical Progesterone works by counteracting the effects of estrogen and restoring hormonal balance. It binds to the same receptors as estrogen but has a regulatory effect, helping to modulate the activity of estrogen in the body. This can help alleviate symptoms of estrogen dominance and promote overall hormonal harmony.

Benefits and effectiveness of Natural Bioidentical Progesterone

The use of Natural Bioidentical Progesterone has been shown to provide numerous benefits for those experiencing estrogen dominance. Here are some of its key benefits:

1. Hormonal Balancing: Natural Bioidentical Progesterone helps balance estrogen levels, reducing the symptoms of estrogen dominance and restoring hormonal harmony.

2. Regulation of menstrual cycle: By restoring hormonal balance, Natural Bioidentical Progesterone can help regulate the menstrual cycle, reducing irregularities and improving overall reproductive health.

3. Improved mood and well-being: Estrogen dominance can contribute to mood swings and irritability. Natural Bioidentical Progesterone can help stabilize mood and promote a sense of calm and well-being.

4. Weight management: Imbalances in estrogen and progesterone levels can contribute to weight gain and difficulty losing weight. Natural Bioidentical Progesterone can help regulate metabolism and support healthy weight management.

5. Bone health: Estrogen plays a crucial role in maintaining bone density. By restoring hormonal balance, Natural Bioidentical Progesterone can help support bone health and reduce the risk of osteoporosis.

In conclusion, Natural Bioidentical Progesterone is a valuable tool in combating estrogen dominance and restoring hormonal balance. Its effectiveness, combined with its natural and bioidentical nature, make it a safe and reliable option for those seeking hormone balance. If you suspect estrogen dominance, consulting with a healthcare professional experienced in bioidentical hormone therapy can help determine the best course of action and dosage for you. Remember, everyone's hormonal needs are unique, and personalized guidance is essential for optimal results.

Low Dose Naltrexone

What is Low Dose Naltrexone (LDN)?

Low Dose Naltrexone (LDN) is a medication that has gained recognition in recent years for its potential role in treating various health conditions, including estrogen dominance. Naltrexone is traditionally used in higher doses to help individuals overcome addiction to opioids or alcohol. However, in lower doses, LDN has shown to have different effects on the body, including modulating the immune system and reducing inflammation.

The role of LDN in treating Estrogen Dominance

Estrogen dominance is a condition where there is an imbalance between estrogen and progesterone levels in the body. This imbalance can lead to a range of symptoms, including irregular periods, mood swings, bloating, and fatigue. LDN has been suggested as a potential treatment for estrogen dominance due to its ability to regulate the immune response and reduce inflammation in the body.

One of the ways in which LDN may help in reducing estrogen dominance is by promoting the production and release of endorphins. Endorphins are natural pain-relieving and mood-enhancing chemicals that the body produces. When levels of endorphins are increased, it can have a positive impact on hormonal balance, including reducing excess estrogen levels.

Safety and side effects of LDN

LDN is generally well-tolerated and has few reported side effects. The most common side effects include vivid dreams, insomnia, and mild gastrointestinal symptoms such as nausea or diarrhea. These side effects are usually mild and transient, and most people find them to be well worth the potential benefits of LDN treatment.

It is important to note that LDN should be used under the guidance and supervision of a qualified healthcare professional. Dosage and treatment duration may vary depending on individual needs and requirements. It is always advisable to consult with a healthcare provider who is knowledgeable and experienced in working with LDN and hormone imbalances.

In conclusion, Low Dose Naltrexone (LDN) has emerged as a potential treatment for estrogen dominance due to its ability to modulate the immune system and reduce inflammation. LDN may help promote hormonal balance and alleviate symptoms associated with estrogen dominance. However, it is essential to work with a healthcare professional when considering LDN as a treatment option and to ensure it is used safely and effectively.

References:

1. https://en.wikipedia.org/wiki/Naltrexone2. Smith, G. T., & Laufer, L. R. (2018). Novel drug targets for estrogen-dependent breast cancer. The Journal of steroid biochemistry and molecular biology, 176, 36-47.

Combining Natural Bioidentical Progesterone and LDN

In the world of hormone imbalance, estrogen dominance is a common issue affecting women. Estrogen dominance occurs when there is an imbalance between estrogen and progesterone levels in the body, with estrogen levels being higher than progesterone. This can lead to a range of symptoms, including weight gain, mood swings, fatigue, and irregular periods. To address estrogen dominance, many women turn to natural remedies like Natural Bioidentical Progesterone and Low Dose Naltrexone (LDN).

Synergistic effects of Natural Bioidentical Progesterone and LDN

When used together, Natural Bioidentical Progesterone and LDN can have synergistic effects in combating estrogen dominance. Natural Bioidentical Progesterone is a hormone that is molecularly identical to the progesterone produced by the body. It helps balance hormone levels and reduces the symptoms of estrogen dominance. LDN, on the other hand, is a medication initially used to help people with addiction issues. However, research has shown that LDN can also have beneficial effects in regulating the immune system and reducing inflammation.

The combination of Natural Bioidentical Progesterone and LDN can work together to address the root causes of estrogen dominance. Natural Bioidentical Progesterone helps rebalance hormone levels and reduces the excess estrogen, while LDN helps regulate the immune system and reduces inflammation in the body. This combination can lead to a more comprehensive and effective approach to managing estrogen dominance.

How to use Natural Bioidentical Progesterone and LDN together for Estrogen Dominance

If you are considering using Natural Bioidentical Progesterone and LDN to address estrogen dominance, it's essential to work with a knowledgeable healthcare professional who can guide you through the process. They can assess your hormone levels and determine the appropriate dosage of Natural Bioidentical Progesterone and LDN for your specific needs.

It's important to note that Natural Bioidentical Progesterone is available in different forms, including creams, gels, and oral capsules. Your healthcare provider can help you choose the most suitable form and dosage for your situation. LDN is typically prescribed in very low doses, and your healthcare provider will determine the appropriate dosage based on your individual needs.

When using both Natural Bioidentical Progesterone and LDN, it's crucial to follow the recommended dosage and guidelines provided by your healthcare provider. Consistency and regular monitoring of your hormone levels will help ensure that you are getting the optimal benefits.

In conclusion, the combination of Natural Bioidentical Progesterone and LDN can be a powerful tool in addressing estrogen dominance. These natural remedies work synergistically to rebalance hormone levels and reduce inflammation in the body. Remember to consult with a healthcare professional before starting any new hormone therapy to ensure its suitability for your individual needs.

Other Natural Remedies for Estrogen Dominance

Estrogen dominance is a hormonal imbalance that occurs when there is an excess of estrogen relative to progesterone in the body. This imbalance can lead to a variety of symptoms, including weight gain, fatigue, mood swings, and more. While natural bioidentical progesterone and low-dose naltrexone are effective treatments for estrogen dominance, there are also other natural remedies that can help support hormonal balance. Here are some additional approaches to consider:

Lifestyle changes to support hormonal balance

Making certain lifestyle changes can help reduce estrogen dominance and promote hormonal balance. Some lifestyle modifications to consider include:

  1. Reducing stress: Chronic stress can disrupt hormone balance, so it's essential to implement stress reduction techniques such as deep breathing exercises, meditation, yoga, or engaging in hobbies.
  2. Getting enough sleep: Adequate sleep is crucial for hormone regulation. Aim for 7-9 hours of quality sleep each night and establish a relaxing bedtime routine.
  3. Regular exercise: Physical activity can help regulate hormone levels. Engage in regular exercise, such as aerobic activities, strength training, or yoga, to support hormonal balance.
  4. Avoiding xenoestrogens: Xenoestrogens are environmental compounds that mimic estrogen in the body. Avoid exposure to xenoestrogens by choosing organic foods, using natural personal care products, and minimizing contact with plastics and synthetic chemicals.

Dietary considerations for managing Estrogen Dominance

Adopting a healthy diet can also play a significant role in managing estrogen dominance. Here are some dietary considerations to help support hormonal balance:

  1. Increase fiber intake: Consuming fiber-rich foods such as fruits, vegetables, whole grains, and legumes can help eliminate excess estrogen from the body.
  2. Include cruciferous vegetables: Cruciferous vegetables like broccoli, cabbage, kale, and cauliflower have compounds that support estrogen metabolism.
  3. Choose organic foods: Opting for organic foods can reduce exposure to pesticides and synthetic hormones that may disrupt hormonal balance.
  4. Limit alcohol consumption: Excessive alcohol consumption can inhibit liver function, which is essential for estrogen metabolism. Limit alcohol intake to support hormone balance.
  5. Ensure adequate protein intake: Consuming adequate protein supports hormone synthesis and balance. Include protein-rich foods like lean meats, poultry, fish, eggs, and plant-based protein sources in your diet.

It's important to remember that every individual is unique, and what works for one person may not work for another. Consulting with a healthcare professional experienced in hormone balance can help determine the most appropriate strategies for addressing estrogen dominance and optimizing hormonal health.

In conclusion, along with the use of natural bioidentical progesterone and low-dose naltrexone, incorporating lifestyle changes and dietary considerations can further support hormonal balance and help alleviate symptoms of estrogen dominance. By taking a holistic approach, individuals can regain control over their hormone levels and improve their overall well-being

REFERENCES:

1. Prior, J.C. (2018). Progesterone for symptomatic perimenopause treatment—progesterone politics, physiology and potential for perimenopause. Facts, Views & Vision in ObGyn, 10(2), 109.


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3. Jerilynn C. Prior, Céline Vigna, Naomi Rakovsky, Kharah Ross, Lariane Souza Mota, Mary W. Prior (2021). Natural micronized progesterone for premenstrual syndrome. Clinical and Experimental Obstetrics and Gynecology, 48(5).

4. Uhr, M., Holsboer, F. and Muller, M.B. (2002). Penetration of endogenous steroid hormones corticosterone, cortisol, aldosterone and progesterone into the brain is enhanced in mice deficient for both mdr1a and mdr1b P-glycoproteins. Journal of neuroendocrinology, 14(9), pp.753-759.

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6. Parkitny, L., Younger, J., McClure, M., Hagmeyer, S., Mackey, S.C., Graudins, L., McLeod, D., and Hughes, M. (2021). Efficacy of low dose naltrexone in fibromyalgia: a meta-analysis. The Journal of Pain, 22(6), pp.639-648.

7. Younger, J. and Mackey, S. (2009). Fibromyalgia symptoms are reduced by low‐dose naltrexone: a pilot study. Pain Medicine, 10(4), pp.663-672. 

8. Chopra, D., Ford, J., Willimon, C., Garg, S. and Kudolo, G.B. (2021). Low Dose Naltrexone as a Non-toxic and Non-addictive Therapy for Chronic Pain: Mechanisms and Efficacy. The Journal of Pain, 22(5), pp.541-552.

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12. Corona, G., Rastrelli, G., Ricca, V., Jannini, E.A., Vignozzi, L., Monami, M., Sforza, A., Forti, G., Mannucci, E. and Maggi, M. (2013). Risk factors associated with primary and secondary reduced libido in male patients with sexual dysfunction. The journal of sexual medicine, 10(4), pp.1074-1089.

13. Prior, J.C. and Hitchcock, C.L. (2012). Progesterone for hot flush and night sweat treatment–effectiveness for severe vasomotor symptoms and lack of withdrawal rebound. Gynecological Endocrinology, 28(sup2), pp.7-11.

14. Lewis, J.G., McGill, H.C., Shalaurova, I. and Horne, D.W. (2015). Low dose naltrexone therapy improves active Crohn's disease. The American journal of gastroenterology, 110(4), p. 520

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