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How Bio-identical Hormones affects the aging process

Richard Nkwenti; R.Ph; IMD; MSHS Integrative Medicine, Ph.D Integrative Medicine; ABAAHP; FAAMFM

Chronic diseases have increased tremendously over the years, impacting the lives of our aging population. These conditions bring both financial and emotional chaos to the medical community, as they are treated with symptom-based medications that do not address the underlying cause of the condition. This is particularly detrimental to older patients, who often have multiple chronic conditions that impact their quality of life. In addition to the physical manifestations of these diseases, patients must also deal with the mental and emotional toll that chronic illness takes on their lives. Our aging population deserves better than to be treated with Band-Aids that do not address the underlying problems. We need to find ways to address the root causes of chronic disease in order to improve the lives of our aging population. it's time we find out why this epidemic continues unchecked?

It is a well-known fact that our population is aging. According to the United Nations, the number of people aged 60 or over is expected to more than double by 2050, reaching 2.1 billion. With longer lifespans comes an increased risk of chronic diseases such as diabetes, heart disease, stroke, Alzheimer's, and immune system disorders. In addition, back pain and sciatica are common problems in older adults. While some of these conditions can be treated with medication, many are resistant to traditional medical interventions. However, recent advances in quantum physics principles and bio-identical hormones offer hope for a new generation of treatments that could improve the quality of life for millions of older adults. quantum physics principles and bio-identical hormones are promising new approaches that show great promise in treating aging-related conditions. By understanding the role that quantum physics plays in the aging process, we can develop new treatments that could potentially improve the quality of life for millions of people.

Pharmaceutical companies have created several symptom-modifying-only drugs throughout the years to help us better manage our chronic illnesses. Unfortunately, these products are limited in their ability to combat chronic dysfunction from an anti-aging perspective. They merely provide short-term relief while also assisting in the orchestration and spread of more serious issues, such as cancer. Low-grade, persistent inflammation that lasts for months or even years is what is known as chronic inflammation. Numerous chronic disorders, including heart disease, arthritis, and diabetes, are associated with this kind of inflammation. Chronic inflammation is undesirable and can injure good tissue, but acute inflammation is a normal reaction of the body to combat infection or repair a wound. Drugs that lessen the symptoms of chronic inflammation may be helpful, but they do not treat the underlying cause. In fact, several of these medications may even increase chronic inflammation by stimulating the development of malignant cells or inhibiting the immune system. These factors make symptom-modifying medications of limited use to an anti-aging specialist who wants to encourage health and stave off disease.

The mitochondria are organelles in charge of energy production in most cells of the human body, including skeletal muscle cells (SMCs). The energy released by the mitochondria is stored in a small molecule called ATP. This energy is then used by the cell to power various biochemical reactions. In addition to ATP production, mitochondria also play a role in lipid and carbohydrate metabolism, as well as calcium homeostasis. Mitochondrial dysfunction has been implicated in a wide variety of diseases, including neurodegenerative diseases, cancer, diabetes, and cardiovascular disease. Furthermore, mitochondrial dysfunction is thought to play a role in the aging process. Acute or chronic fatigue is often one of the first symptoms of mitochondrial dysfunction. If left unchecked, mitochondrial dysfunction can lead to a wide range of serious health problems. Therefore, it is important to be aware of the signs and symptoms of mitochondrial dysfunction and to seek medical help if you experience any unexplained fatigue or other unexplained health issues.

The overwhelming body of available scientific evidence points in the direction of the conclusion that nutritional supplements can play a significant and unmistakably positive role in the treatment of chronic illnesses, chronic tiredness, and other diseases and conditions associated with aging. It would be foolish to disregard the possible advantages of dietary supplement supplementation in favor of other less effective or unproven therapies in light of this research. It's time to recognize how effective dietary supplements may be in regaining one's health and vigor. In the prevention and treatment of chronic illnesses, chronic fatigue, and other aging-related diseases and disorders, dietary supplement supplementation can play a significant role, according to a review of more than 500 scientific research that were published in major medical publications. It has been demonstrated that the advantages of dietary supplements are most effective when used in conjunction with lifestyle modifications, such as a healthy diet and frequent exercise. There is no one-size-fits-all method to treating chronic disorders but using nutritional supplements as part of an all-encompassing treatment plan can significantly enhance the health and wellbeing of those who suffer from these conditions.

Scientists are still trying to fully comprehend all of the components that contribute to the complex aging process. How the skin ages is one topic of discussion. Some experts think genetics is the most important component, while others think environmental and hormonal variables are more important. Both sides of the debate can be supported by some evidence. Studies have demonstrated, for instance, that those with a history of sun exposure have a tendency to have more wrinkles and age spots than those without such a history. This shows that the environment may affect how quickly skin ages. Other studies, however, have revealed a connection between specific genes and a higher incidence of wrinkles or other aging-related skin disorders. This implies that heredity might possibly play a role. There is currently no conclusive explanation for how the skin ages. But researchers are still looking at this issue to learn more about all the variables at play. People can take precautions like using sunscreen and refraining from smoking in the meantime to help preserve their skin from premature aging.

Estrogens are important players in the pathophysiology of many chronic medical disorders, including obesity, osteoarthritis, inflammation, and skin aging and wound healing. The ovaries and the adrenal glands create the hormones known as estrogens. Estradiol, estrone, and estriol are the three different forms of estrogens. The most active type of estrogen is estradiol. It contributes to the growth of bones as well as the development of secondary sex traits and female sex organs. The least potent type of estrogen is estrone. It contributes to the growth of breast tissue, menstrual cycle control, and pregnancy maintenance. During pregnancy, a lot of estriol, a weak type of estrogen, is produced. It helps to thicken the uterine lining and guards against miscarriages. Numerous chronic diseases, including heart disease, diabetes, and stroke, are at risk due to obesity. By promoting fat accumulation and reducing energy expenditure, estrogens contribute to the emergence of obesity. Estrogen is produced by fat cells, and this causes a feedback loop that makes fat storage even more prevalent. Additionally, estrogens make it harder for the body to utilize glucose for energy by increasing insulin resistance.

According to the World Health Organization, chronic diseases are to blame for some of the most prevalent and expensive health issues, such as diabetes, cancer, heart disease, and stroke. In actuality, chronic diseases account for approximately one-third of all annual deaths, making them the world's biggest cause of mortality and disability. More than 1.7 million individuals die from chronic diseases each year in the United States alone, and the healthcare system incurs billions of dollars in costs for treatment and lost productivity. The good news is that chronic conditions can be avoided. People can significantly lower their chance of having these disorders by changing their lifestyles to include eating a nutritious diet, exercising frequently, and quitting smoking. To achieve lasting changes, it is frequently important to seek expert assistance because breaking long-standing patterns can be challenging. Fortunately, there are plenty of tools at hand to support people in making these essential adjustments. People with chronic diseases can enjoy long, healthy lives if they receive the proper support.

In the body's youth and early adulthood, dehydroepiandrosterone (DHEA), a naturally occurring steroid hormone, is present in high concentrations. However, DHEA levels decrease with aging, and low DHEA levels have been associated to a number of age-related changes in people, such as accelerated aging, cognitive decline, and cardiovascular disease. DHEA has earned the nicknames "super hormone" and "magic bullet" for anti-aging because some specialists think that supplementing with it may be able to reverse some of these age-related alterations. It's vital to remember that additional research is required to validate the efficacy of DHEA because the study of its positive benefits is still in its early phases.

References:

1. Emmerson, E. and Hardman, M.J. (2012) The Role of Estrogen Deficiency in Skin Ageing and Wound Healing. Biogerontology, 13, 3-20.
http://dx.doi.org/10.1007/s10522-011-9322-y 

2. Martín-Millán M, Castañeda S. Estrogens, osteoarthritis and inflammation. Joint Bone Spine. 2013 Jul;80(4):368-73. doi: 10.1016/j.jbspin.2012.11.008. Epub 2013 Jan 23. PMID: 23352515. 

3. Lizcano F, Guzmán G. Estrogen Deficiency and the Origin of Obesity during Menopause. Biomed Res Int. 2014;2014:757461. doi: 10.1155/2014/757461. Epub 2014 Mar 6. PMID: 24734243; PMCID: PMC3964739.