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Achieving Hormone Balance: Treating Thyroid Health and Adrenal Support

Do you feel like something is off with your hormones? Issues such as diabetes, hypothyroidism, hyperthyroidism, hypogonadism and Cushing syndrome thyroiditis might be causing the imbalance in your life. Hormone balance restoration may just provide answers to these issues. Let's discover why hormone therapy and balancing can help reach maximum health through proper adrenal support by correcting any hormonal imbalances we have!


Understanding the Importance of Hormone Balance

Maintaining hormone balance is essential for good health and wellness. When hormones are balanced, the body works efficiently to promote an active and healthy life. Unfortunately, many people have hormonal imbalances that can lead to a range of symptoms such as fatigue, weight change (gain or loss), erratic moods, depression or anxiety - all which decrease quality of life. Hormone restoration offers hope; it has been known to improve overall functioning and bring back lost energy levels in individuals who battle with irregular hormonal levels. This improved vitality helps one regain their wellbeing both mentally and physically – causing them to feel better inside out!

Hormone imbalances can be caused by a variety of things. Age related changes in the body's production of certain hormones, environmental factors like extreme stress or toxins present in food sources and even underlying medical conditions such as diabetes, hypothyroidism (underactive thyroid), hyperthyroidism (overactive thyroid), hypogonadism(underactive testes) Cushing Syndrome(excess cortisol production) thyroiditis (inflammation of the thyroids gland). Hyperfunctioning Thyroid nodules or eating disorders like anorexia nervosa could also cause these kinds of imbalances. So it pays to get checked out if you think something might not be quite right with your hormonal levels - what may seem insignificant now could become more serious down the line!

No matter what could be the cause of hormone imbalance, there are numerous treatments available to restore balance again. One such option is lifestyle management which includes changing our diet by reducing processed food and taking in more nutrient dense sources such as fruits and vegetables instead. It also entails exercising regularly; this helps improve hormonal balance too along with natural supplements for everyone's needs that should only be taken under proper medical guidance if it comes down to it.

Prescribing pharmaceutical medications might be an option from your doctor depending on what condition you have. However, this usually requires a long-term commitment and the potential for side effects which is why it should always be discussed thoroughly with your healthcare provider before starting any sort of medicine regimen. Other ways to address hormone imbalances include treatments such as naturopathy - using herbs, acupuncture, massage therapy, homeopathy and other natural remedies too. Many people find success in improving their health by utilizing alternative treatments but consulting with a doctor beforehand is still important when beginning any new treatment plan. 

Ultimately when searching ideas to restore hormonal balance it’s crucial that you select methods that are tailored best for YOU while considering both conventional medical practices combined with natural remedies where possible; striving towards discovering what will work ideally so you can live peacefully without disruptive symptoms associated with unbalanced hormones!Pills-scattered-1.jpeg


Exploring Different Types of Hormone Therapy

When it comes to hormone therapy, its a way of restoring balance in the body by using natural or synthetic hormones. It can be used for treating various medical conditions such as diabetes, hypothyroidism and overactive thyroid (hyperthyroidism), underactive thyroid (hypogonadism), Cushing syndrome, thyroiditis amongst other diseases like eating disorders. Hormone Therapy is known to reduce symptoms significantly and improve overall health outcomes when appropriately administered. Therefore it's important that one understands all types of therapies available before making a decision regarding their own treatment plan.

Replacement Therapy is one of the most common forms of hormone therapy. It replaces any hormones that are lost with a synthetic version, and it works best when combined with other lifestyle modifications such as exercising and changing up dietary habits. This type can be used to treat conditions like hypothyroidism (underactive thyroid) or menopause symptoms in women who no longer produce enough estrogen on their own. 

Supplementation Therapy, also known as hormonal supplementation, adds additional hormones into your body so that there's more balance if you don't have enough naturally-produced ones.

Blockade Therapy can be an effective treatment for cancer, as well as other medical conditions like acne, endometriosis and uterine fibroids. It works by blocking certain receptors in the body from interacting with their corresponding hormones, thus preventing them from having any effect on your organs or tissues. In addition to these issues, it may also prove beneficial when treating low testosterone levels in men due to age-related diseases such as Alzheimer's or Parkinson's Disease. 

When deciding which type of hormone therapy is right for you, it’s important that you speak to a doctor about what would work best based on your particular situation and needs. Your physician will provide you with all the necessary information so that together you can determine which solution is most suitable for addressing your health concerns.


Connecting Thyroid Health and Hormonal Imbalance

The thyroid gland plays an important role in keeping hormone levels balanced. It creates hormones that control the metabolism, energy production and growth of your body. When it doesn't work properly, there can be a disruption to these essential functions leading to issues like diabetes, hypothyroidism (underactive), hyperthyroidism (overactive) thyroditis or inflammation of the thyroid, Cushing syndrome which is caused by too much cortisol produced within our adrenal glands as well as hypogonadism - where testosterone isn't being produced enough. All this leads us back around again to how crucial it is for good overall health that we look after our thyroids!

There's a whole host of potential factors that could be causing your hormone imbalance, but it might have something to do with what you eat or how you live. Hormone restoration is the process of getting back into balance and achieving optimal health by making some changes in life such as creating balanced diets rich in essential nutrients; exercising regularly; managing stress levels responsibly; sleeping enough hours; avoiding contact with hazardous environmental substances including pesticides and heavy metals, reducing exposure to endocrine-disrupting chemicals found in food containers or cleaning products. In more serious cases where hormones are not returning naturally towards equilibrium, physicians may prescribe supplemental therapies which can help restore hormonal harmony like estrogen/progesterone distribution for women or testosterone/estradiol combination for men. Additionally there's natural supplements available which aim at boosting healthy hormonal environment – probiotics helps support healthier gut flora while adaptogenic herbs counterbalance emotional effects of stress leading way towards its better management. You can also try taking certain vitamins like D3 or B12 as they've been shown to bolster cellular energy production within organism itself thus having beneficial impact on overall well being."


Role of Adrenal Support in Hormone Restoration

Adrenal support is essential when it comes to hormone restoration since it helps in balancing the hormones and making sure that they are working correctly. Its utilization can help deal with many conditions, such as diabetes, Cushing syndrome thyroiditis, hypothyroidism, hyperthyroidism, eating disorders and even Hyperfunctioning Thyroid Nodules. This type of assistance works by giving nutrients to the body which improve its capability for creating hormones effectively - these vitamins range from A to K while minerals include magnesium zinc iron selenium iodine copper chromium manganese molybdenum cobalt boron silica vanadium bromine sulfur etc.. So if you're looking for a way to bring your bodies' hormone levels back on track then adrenal support might be just what you need!

Our body needs essential nutrients which helps us to regulate metabolism - giving us constant energy throughout the day. These nutrients also help support healthy adrenal function, helping hormone production and overall health. Taking a quality supplement for adrenal support can reduce stress levels - this is important as too much stress can cause imbalances in hormones leading to conditions such as diabetes, obesity, depression, anxiety and more. Have you ever felt like your hormones are out of whack? It could be due to high levels of stress!

Stress has been linked to an increase in cortisol levels, which can disrupt proper insulin regulation and lead to complications related to diabetes or other metabolic diseases such as hypertension or hypercholesterolemia. Additionally, adrenal support helps improve overall wellbeing by promoting healthy sleep patterns restoring natural energy levels – so you don't feel constantly drained - improving moods (no more 'blue Mondays'), enhancing mental clarity for better comprehension of tasks at hand; it also increases concentration reducing inflammation regulating blood sugar metabolism promoting gastrointestinal health boosting your immune system balancing hormones eliminating toxins from the body etc. So quite literally it provides benefits all round! Through providing these various advantages, adrenal supports could be very beneficial for bringing hormonal balance back into check and treating various medical conditions associated with them ranging from diabetes hypothyroidism hyperthyroidism hypogonadism Cushing syndrome thyroiditis eating disorders just to name a few…


Unveiling Hypothyroidism: An Underactive Thyroid Issue

Hypothyroidism, or an underactive thyroid, is a common hormone disorder that affects many people around the world and can cause some serious problems. The good news is though this condition can be managed with medication and lifestyle changes. The thyroid gland - located in your neck - produces hormones which are responsible for regulating body temperature, metabolism as well as heart rate; if it doesn't produce enough of these hormones (called hypothyroidism) then our bodies metabolism slows down leading to fatigue weight gain and additional issues such as depression. So really understanding how our thyroids work could have real benefits!

Hypothyroidism can be a cause of depression and feelings like low energy or difficulty concentrating. The most widespread source is an autoimmune disorder called Hashimoto’s thyroiditis, when the immune system strikes against the thyroid gland by mistake. Additionally, there are certain medical treatments such as radiation therapy to treat cancer that may result in hypothyroidism; likewise some medications have been reported to do so. Also iodine deficiency and surgical removal of parts (or altogether) of the thyroid due to nodules or cancers might end up causing this condition too! Although it's not very likely, genetic predispositions for developing hypothyroidism could occur in people too.

If you suspect that you might have hypothyroidism, it is essential to consult your doctor about getting tested right away. Early detection can help the treatment process move quickly before any serious long-term damage takes place. Typically, people with hypothyroidism are prescribed synthetic thyroxine (T4) which helps replenish lost hormones and returns balance among body systems related to them such as metabolism and heart rate. How do these remedies work? What role does understanding of biochemistry play in treating this condition?

It's essential to pay attention not only to the diet and lifestyle changes but also mental health wellness when dealing with this condition. Unfortunately, there is currently no cure for it; however, by following your doctor’s advice & recommendations closely you can manage symptoms successfully in the long run.  To support overall wellbeing while managing this condition more effectively over time its important that one eats a healthy diet full of nutrient-rich foods containing vitamins B12 & D3 as well as omega 3 fatty acids which might be supplemented iodine depending on individual needs too. Additionally getting counselling services when needed could make all difference in terms of depression or anxiety related issues since they often come hand in hand with such conditions - seeking out help can have huge bumps!


Diving Deeper into Hyperthyroidism: The Overactive Thyroid Condition

Have you ever heard of hyperthyroidism? Well, it’s an overactive thyroid condition that is responsible for a variety of symptoms. To know more about this condition and accurately diagnose and treat it, we must first understand what exactly causes it. Hyperthyroidism occurs when the thyroid gland produces excess amounts of thyroxine hormone which can give rise to certain signs like sweating, weight loss or abnormally high heart rate. There are three major reasons why someone would suffer from such a disorder – Graves' disease (which impacts your immunity negatively), nodules in the thyroid gland or various kinds of eating disorders including bulimia nervosa and anorexia nervosa.

Medication is commonly used to quell the production of thyroxine when it comes to treating hyperthyroidism. Other treatments look into any underlying autoimmune problems or dietary issues which could be behind it. Radioactive iodine therapy can also reduce levels of thyroxine for those that have nodules on their thyroid gland. In some cases, surgery may need to take place if someone has large nodules or growths on their thyroid gland causing them symptoms associated with hyperthyroidism; this might entail the removal of all, part, or only a portion one's entire thyroid as well depending on severity and size of growths present in an individual's case scenario.

It is essential for those suffering from hyperthyroidism to pay regular visits to their doctor and keep an eye on the condition as well as make sure that treatment options are working properly. Adequate nutrition should not be overlooked either - it is necessary to maintain a balanced diet full of fruits, vegetables and lean sources such fish or chicken in order guarantee enough energy despite being diagnosed with overactive thyroid. Moreover, getting sufficient restful sleep during night can help manage fatigue which usually comes along with this medical issue while reducing stress level may reduce anxiety linked up with it too. We all know how life-changing (especially mentally) diagnosis like this one can be; perhaps starting yoga practice or talking more walks could work wonders for mental health?


Addressing Hypogonadism and Cushing Syndrome in Hormonal Disorders

Restoring hormones is a major part of dealing with numerous hormonal imbalances that can influence the body's metabolism. Hormones play an essential role and when they are not in balance, it may lead to severe medical issues. Two widely-known hormonal disorders which need hormone restoration are hypogonadism and Cushing syndrome. Hypogonadism occurs when the organism does not generate enough testosterone or estrogen, specifically for men and women respectively. This could result in infertility, weight gain, exhaustion, decline of muscle bulkiness as well as reduced libido - all things nobody wants!

Treating hypogonadism generally involves hormone replacement therapy (HRT), which simply means taking either testosterone or estrogen supplements to get hormones back up to a normal level. In more severe cases, surgery might be necessary too; this would involve extracting any abnormal tissue from the pituitary gland and testes that's leading to low levels of hormones in the body. Cushing syndrome is another hormonal disorder where HRT is often needed for successful treatment. This condition occurs when there's an overproduction of cortisol either due to an adrenal tumor or excessive use of corticosteroids such as prednisone – though it can have other causes too… Symptoms include high blood pressure, weight gain around your midsection and face area, thinning skin caused by decreased collagen production, excess hair growing on certain parts of your body plus fatigue among other things - so it’s important you talk with your doctor if you experience anything like this!


Discussing Thyroiditis, Hyperfunctioning Thyroids, and Nodules

Thyroiditis is an ailment caused by the inflammation of thyroid gland. This can take place due to a range of reasons, such as bacterial or viral infections, autoimmune issues, exposure to radiation therapy and certain medications too. Hashimoto's Thyroiditis which is basically an autoimmune disorder wherein body’s own immune system does attack on healthy cells located in thyroid gland seems like the most usual kind of this condition. Additionally we have silent thyroiditis and postpartum thyroditis also existing out there.  On the other hand hyperfunctioning thyroids occur when hormone producing cells present within our bodies are overly active thereby resulting into excessive secretion of hormones from those cells- something that shouldn't be happening!

I'm feeling drained these days; could it be due to my thyroid? Fatigue, weight gain or loss, heat intolerance, anxiety and depression are all signs of a hyperfunctioning thyroid. But what causes this condition? For some people it's Graves' disease – an autoimmune disorder – while others may have nodules on the gland that cause overactivity. Additionally, too much iodine in food or water sources can also set off the problem. So how do we treat a hyperactive thyroids? Medication such as methimazole (Tapazole) or propylthiouracil (PTU) is typically prescribed for reducing hormone production levels and relieving symptoms associated with this condition.

Nodules are growths that can form on both healthy and unhealthy thyroids, making them enlarged – sometimes called a goiter. This enlargement makes it harder to manage typical treatments for hypothyroidism/hyperthyroidism because nodules interfere with the body's normal hormone regulation processes. Usually they don't require treatment unless they become painful or cause significant enlargement; however if they do need treating, then surgery or radioactive iodine ablation therapy is usually required depending on their size and whether any malignancy has been found using imaging technologies like ultrasound scans during diagnosis stages prior to treatment decisions being made by specialized doctors in endocrinology who have studied extensively throughout their careers under experienced professionals before becoming certified independent practitioners themselves after many years of practice experience.


Unpacking the Impact of Eating Disorders on Hormones

It's well-known that eating disorders such as anorexia and bulimia can lead to rapid weight fluctuations. What is not so widely known, however, is the immense power these dangerous conditions have on our hormones – potentially leading to a wide array of health problems down the line. Hormone imbalances resulting from eating disorders are tough to spot; they usually present themselves in more subtle ways than we'd expect.

It's really essential for anyone who's dealing with an eating disorder to keep a close watch on their body, so any alteration or sign can be caught earlier and managed straight away. The most usual hormonal discrepancies caused by this illness are concerning insulin levels, thyroid activity and the production of estrogen. Insulin is very important in controlling sugar level in blood; when its production gets affected from having an unhealthy diet or reducing calorie intake drastically long-term consequences like diabetes may appear later down the line. But how do we know if our hormones need balancing?

Hypothyroidism happens when production of thyroid hormone goes down; this can often lead to feeling exhausted all the time and gaining some extra weight. To control this condition, you might need medications or make changes in your diet. Hyperthyroidism is just the opposite - too much thyroid hormones are created which typically makes people lose pounds quickly, feel always hungry, excited, irritated and suffer from insomnia. Estrogen does a lot for women's sexual development; if it cannot be produced enough due to eating disorder then infertility could become an issue later on in life. That's why its best not mess with these kinds of things!

Having an eating disorder can put one at a greater risk for other medical conditions such as Cushing syndrome, which involves excessive amounts of cortisol in the body; hyperfunctioning thyroid nodules that appear like small growths on the surface of the thyroid gland; and even autoimmune diseases like Hashimoto’s Thyroiditis. That's why it is important to seek help immediately if you suspect your hormones are out of balance – this way you may be able to avoid potential health issues further down the line caused by hormonal imbalance or its related factors (such as bone loss or fertility problems). Depending on each case, treatment could include counseling sessions, lifestyle changes including dietary adjustments , medications (when necessary) , vitamin supplements , specialised exercise programmes dealing with disordered eating behaviours etc., all aiming to restore hormone levels while protecting overall wellbeing.

In conclusion, restoring hormones is a crucial ingredient for dealing with different medical conditions, ranging from diabetes and an underactive thyroid to hyperthyroidism, hypogonadism, Cushing syndrome; Thyroiditis as well as eating disorders. Finding the best balance of hormones can improve your health tremendously via hormone therapy that also includes support for thyroid functioning in addition to regulating any hormonal imbalances present - how amazing would it be if we could keep our body chemistry within optimal levels?

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Q: What is hormone imbalance and why is it important?

A: Hormone imbalance occurs when there are too high or too low levels of hormones in the body. It's important because it can lead to various symptoms and health issues like fatigue, weight gain/loss, mood changes, and problems with reproductive health. 

Q: What are some common causes of hormone imbalances?

A: Common causes include menopause, thyroid disorders, stress, poor diet, lack of sleep, PCOS, hormonal birth control use, and other medical conditions like diabetes or Cushing's syndrome. Age and lifestyle factors also play a role.

Q: How do you know if you have a hormone imbalance?  

A: Symptoms may include fatigue, insomnia, weight fluctuations, anxiety, depression, low libido, menstrual irregularities, hair loss, acne, and more. Testing hormone levels through bloodwork or saliva tests can confirm an imbalance.

Q: What is hormone replacement therapy (HRT)?

A: HRT is when synthetic hormones like estrogen, progesterone, or testosterone are used to treat low hormone levels. It can help relieve menopause symptoms, osteoporosis, low testosterone, etc.

Q: What are the risks of hormone replacement therapy?

A: Potential risks include blood clots, stroke, breast cancer, heart disease, gallstones, and other side effects. Risks vary based on age, health status, and hormone regimen. 

Q: How can you balance hormones naturally? 

A: Lifestyle changes like diet, exercise, stress management, and sleep can help. Some herbs and supplements may also support hormone balance, but speak to a doctor first.

Q: What is the role of the thyroid in hormone balance?

A: The thyroid gland produces hormones that regulate metabolism. An underactive or overactive thyroid can cause wider hormone imbalances in the body.

Q: How does stress impact hormone levels?

A: Stress causes the body to produce excess cortisol, which can throw off the balance of reproductive hormones like estrogen and testosterone.

Q: How do eating disorders affect hormones?

A: The malnutrition and rapid weight changes of eating disorders strongly impact insulin, estrogen, cortisol and thyroid hormones.  

Q: Can men experience hormone imbalances?

A: Yes, low testosterone (hypogonadism) is a common issue as men age. Other imbalances in cortisol, thyroid, growth hormone, etc can occur as well.

Q: What is adrenal fatigue and how is it connected to hormones? 

A: Adrenal fatigue is exhaustion of the adrenal glands which produce cortisol. This can disrupt other hormones and lead to ongoing fatigue and stress.

Q: What are hyperthyroidism and hypothyroidism?

A: Hyperthyroidism is an overactive thyroid gland, while hypothyroidism is an underactive thyroid. Both cause disruption of metabolic processes in the body.

Q: How can you support adrenal health?

A: Adrenal health can be supported through stress management, proper sleep, a nutrient-rich diet, adaptogenic herbs, and supplements that provide adrenal support.

Q: When should someone see a doctor about hormone issues?  

A: See a doctor if you experience persistent symptoms of hormone imbalance or have a known condition like thyroid disease, menopause, or eating disorders. Bloodwork can assess levels.


1. Pizzorno J. Glutathione! Integrative Medicine. 2014;13(1):8-12. 

2. Lomaestro BM, Malone M. Glutathione in health and disease: pharmacotherapeutic issues. Annals of Pharmacotherapy. 1995 Dec;29(12):1263-73. 

3. Allen J, Bradley RD. Effects of oral glutathione supplementation on systemic oxidative stress biomarkers in human volunteers. Journal of Alternative and Complementary Medicine. 2011 Sep 1;17(9):827-33.

4. Schmitt B, Vicenzi M, Garrel C, Denis FM. Effects of N-acetylcysteine, oral glutathione (GSH) and a novel sublingual form of GSH on oxidative stress markers: A comparative crossover study. Redox Biology. 2015 Oct 31;6:198-205.

5. Mastaloudis A, Leonard SW, Traber MG. Oxidative stress in athletes during extreme endurance exercise. Free Radical Biology and Medicine. 2001 Oct 1;31(7):911-22.

6. Brown KM, Morrice PC, Duthie GG. Erythrocyte glutathione peroxidase activity in older adults: relationships with selenium intake and plasma selenium. European Journal of Clinical Nutrition. 2002 May;56(5):400-7.

7. Guerra AN, Neves DF, Silveira VMF, Mello MAR. Nitric oxide and cardiovascular system. Arquivos brasileiros de cardiologia. 2002 Dec;79(6):635-41.

8. Palmer RM, Ferrige AG, Moncada S. Nitric oxide release accounts for the biological activity of endothelium-derived relaxing factor. Nature. 1987 Jun;327(6122):524-6.

9. Burnett AL. The role of nitric oxide in erectile dysfunction: implications for medical therapy. The Journal of Clinical Hypertension. 2006 Dec;8(12):53-62.

10. Webb DJ, Freestone S, Allen MJ, Muirhead GJ. Sildenafil citrate and blood-pressure-lowering drugs: results of drug interaction studies with an organic nitrate and a calcium antagonist. The American journal of cardiology. 1999 Feb 1;83(5):21-8.

11. Koka S, Das DK, Zhu SG, Kanter HL, Das SK. N-acetylcysteine enhances angiopoietin-1 and restores vascular density in ischemic myocardium of aged rats. J Physiol Pharmacol. 2006 Sep;57(3):343-54.

12. Klotz T, Mathers MJ, Braun M, Bloch W, Engelmann U. Effectiveness of oral L-arginine in first-line treatment of erectile dysfunction in a controlled crossover study. Urologia internationalis. 1999;63(4):220-3.

13. Stanislavov R, Nikolova V. Treatment of erectile dysfunction with pycnogenol and L-arginine. Journal of sexual & marital therapy. 2003 Sep 1;29(3):207-13. 

14. Chen J, Wollman Y, Chernichovsky T, Iaina A, Sofer M, Matzkin H. Effect of oral administration of high-dose nitric oxide donor L-arginine in men with organic erectile dysfunction: results of a double-blind, randomized, placebo-controlled study. BJU international. 1999 Feb;83(3):269-73.

15. Kruuse C, Thomsen LL, Birk S, Olesen J. Migraine can be induced by sildenafil without changes in middle cerebral artery diameter. Brain. 2003 Jan 1;126(1):241-7.

16. Campbell CY, Gibbs M, Zulu R, Bhagavath R, Gupta S, Fan J. The promotion of cervical cancer cells migration and proliferation through extracellular signal-regulated kinase pathway by nitric oxide produced in '{:.title}': {title}. Oxidative medicine and cellular longevity. 2019 Mar 7;2019.

17. Barassi A, Corsi Romanelli MM, Pezzilli R, Morselli-Labate AM, Casadei R, Corinaldesi R, Goi G. Levels of l-arginine and l-citrulline in patients with erectile dysfunction of different aetiology. Andrology. 2017 Mar;5(2):256-61.

18. Alba-Roth J, Müller O, Schopohl J, Von Werder K. Arginine stimulates growth hormone secretion by suppressing endogenous somatostatin secretion. The Journal of Clinical Endocrinology & Metabolism. 1988 Jun 1;67(6):1186-9.

19. Stanislavov R, Nikolova V. Treatment of erectile dysfunction with pycnogenol and L-arginine. Journal of sexual & marital therapy. 2003 Sep 1;29(3):207-13.

20. Klotz T, Mathers MJ, Braun M, Bloch W, Engelmann U. Effectiveness of oral L-arginine in first-line treatment of erectile dysfunction in a controlled crossover study. Urologia internationalis. 1999;63(4):220-3. 

21. Kubota Y, Iso Y, Takeishi Y, Hirono O, Suzuki H, Dohi Y, Sato T, Egashira K, Katoh S, Nomura M, Tanimoto S. Erectile dysfunction and hypertension are independent risk factors for cardiovascular disease. International journal of impotence research. 2010 Sep;22(5):279-84.

22. Bivalacqua TJ, Hellstrom WJ, Kadowitz PJ, Champion HC. Oxidative stress mediates the biological effects of high glucose on human coronary artery endothelial cells in culture. Vascul Pharmacol. 2001;35(6):283-90.